- 询价
- BIO-RAD
- MCA2345B
- 2025年10月17日
- F
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2a
- 形态：
Purified IgG conjugated to biotin - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Biotin
- 适应物种：
Mouse
- 保质期：
自发货之日起 12 个月
- 目录编号：
H207-1082
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
F
- 浓度：
IgG concentration 0.1 mg/ml
- 抗体名：
CD26 antibody | H207-1082
- 规格：
0.1 mg
Rat anti Mouse CD26 antibody, clone H207-1082 recognizes mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma.
The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.
The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | Neat |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
-
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
The Fc region of monoclonal antibodies may bind to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/BUF041B).
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文献和实验该产品被引用文献
References for CD26 antibody
- David, F. et al. (1993) Identification of serine 624, aspartic acid 702, and histidine 734 as the catalytic triad residues of mouse dipeptidyl-peptidase IV (CD26). A member of a novel family of nonclassical serine hydrolases.
J Biol Chem. 268:17247-52. - Marguet, D. et al. (2000) Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26.
Proc Natl Acad Sci U S A. 97:6874-9.
Further Reading
- Vivier, I. et al. (1991) Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV).
J Immunol. 147 (2): 447-54.
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文献支持
Rat anti Mouse CD26:Biotin，clone H207-1082
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