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- 亚型:
IgG1
- 形态:
Purified IgG - liquid
- 克隆性:
Monoclonal Antibody
- 标记物:
Purified
- 适应物种:
Bovine
- 保质期:
自发货之日起 12 个月
- 目录编号:
CC69
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
F, IP
- 浓度:
IgG concentration 1.0 mg/ml
- 抗体名:
CD26 antibody | CC69
- 规格:
0.25 mg
Mouse anti Bovine CD26 antibody, clone CC69 recognizes bovine Dipeptidyl peptidase 4, also known as CD26, WC10, Adenosine deaminase complexing protein or Activation molecule 3 (Lee et al. 2001). Bovine CD26 is a 765 amino acid single pass type II transmembrane glycoprotein which can be cleaved between residues 37-38 to release a soluble form of the protein. CD26 can exist as a monomer, forms a homodimer for optimal dipeptidase activity or it can form a heterodimer with seprase.
CD26 is expressed by a subpopulation of CD2+ T cells, dendritic cells and weakly by most B cells and is also seen on some non-haematopoietic cells, especially gut epithelium. Myeloid cells and the majority of WC1+ve T cells do not express CD26.
CD26 is expressed by a subpopulation of CD2+ T cells, dendritic cells and weakly by most B cells and is also seen on some non-haematopoietic cells, especially gut epithelium. Myeloid cells and the majority of WC1+ve T cells do not express CD26.
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | 1/50 | 1/200 |
| Immunoprecipitation | ✓ |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
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文献和实验该产品被引用文献
References for CD26 antibody
- Howard, C.J. & Naessens, J. (1993) Summary of workshop findings for cattle (tables 1 and 2).
Vet Immunol Immunopathol. 39 (1-3): 25-47. - Naessens, J. et al. (1993) Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants.
Vet Immunol Immunopathol. 39 (1-3): 283-90. - Epardaud, M. et al. (2004) Enrichment for a CD26hi SIRP- subset in lymph dendritic cells from the upper aero-digestive tract.
J Leukoc Biol. 76: 553-61. - Contreras, V. et al. (2010) Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species.
J Immunol. 185: 3313-25. - Ferret-Bernard, S. et al. (2010) Cellular and molecular mechanisms underlying the strong neonatal IL-12 response of lamb mesenteric lymph node cells to R-848.
PLoS One. 5: e13705. - Fries, P.N. et al. (2011) Age-related changes in the distribution and frequency of myeloid and T cell populations in the small intestine of calves.
Cell Immunol. 271: 428-37. - Fries, P. et al. (2011) Mucosal dendritic cell subpopulations in the small intestine of newborn calves.
Dev Comp Immunol. 35 (10): 1040-51. - Contreras, V. et al. (2012) Canine recombinant adenovirus vector induces an immunogenicity-related gene expression profile in skin-migrated CD11b⁺ -type DCs.
PLoS One. 7 (12): e52513.
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Mouse anti Bovine CD26,clone CC69
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