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- 应用范围:
产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-6840R |
| 英文名称 | IEX1 Rabbit pAb |
| 中文名称 | 分化相关基因2蛋白/立即早期反应蛋白抗体 |
| 英文别名 | IEX1; PRG1; Anti death protein; Differentiation dependent gene 2 protein; DIF 2; DIF2; Differentiation dependent gene 2; Differentiation dependent gene 2 protein; Differentiation-dependent gene 2 protein; Expressed in pancreatic carcinoma; GLY 96; GLY96; Gly96 mouse homolog of; IER 3; IER3; IEX 1; IEX 1L; IEX1_HUMAN; IEX1L; Immediate early protein GLY96; Immediate early response 3; Immediate early response 3 protein; Immediately early gene X 1; PACAP responsive gene 1; PACAP responsive gene 1 protein; PACAP-responsive gene 1 protein; PRG 1; Protein DIF 2; Protein DIF-2; Protein PRG1; Radiation-inducible immediate-early gene IEX-1. |
| 产品应用 | ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 17 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins Stem Cells > Cancer Stem Cells > Intracellular |
| 亚基 | Interacts with the PPP2R5C-PP2A holoenzyme and ERK kinases; regulates ERK dephosphorylation. |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein. |
| 翻译后修饰 | Glycosylated. |
| 相似性 | Belongs to the IER3 family. |
| 功能 | May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008]. |
| 应用 | 推荐稀释比例 |
| {ELISA} | {1:5000-10000} |
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文献和实验该产品被引用文献
[IF={{ 5.3 }}] {Wang Qi. et al. Comprehensive analysis of bulk, single-cell RNA sequencing, and spatial transcriptomics revealed IER3 for predicting malignant progression and immunotherapy efficacy in glioma. CANCER CELL INT. 2024 Dec;24(1):1-15} {IF} {Human}
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IEX1 Rabbit pAb(bs-6840R)-50ul/100ul/200ul
¥1180 - 2800





