- ￥1880
- Bioss
- bsm-30152A
- 2025年10月16日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
GLDC Rabbit pAb(bs-13370R)-50ul/100ul/200ul
￥1180
GXYLT2 Rabbit pAb(bs-16377R)-50ul/100ul/200ul
￥1180KDEL Rabbit pAb(bs-6940R)-50ul/100ul/200ul
￥1180
phospho-NFKB1 (Ser373) Rabbit pAb, PE-Cy5.5 conjugated(bs-20075R-PE-Cy5.5)-100ul
￥2980Endothelial lipase Rabbit pAb, Biotin conjugated(bs-10188R-Bio)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ug
| 产品编号 | bsm-30152A |
| 英文名称 | mouse CD4 Rat mAb |
| 中文名称 | 小鼠CD4单克隆抗体 |
| 英文别名 | CD4(L3T4); CD4 antigen(p55); CD4 Antigen; CD4 molecule; CD4 Receptor; CD4+Lymphocyte deficiency, included; CD4mut; L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; MGC165891; p55; T Cell Antigen T4; T cell antigen T4/LEU3; T cell differentiation antigen L3T4; T cell OKT4 deficiency, included; T cell surface antigen T4/Leu 3; T cell surface antigen T4/Leu3; T Cell Surface Glycoprotein CD4; W3/25; W3/25 antigen; T-cell surface glycoprotein CD4 isoform 1 precursor; CD4_MOUSE. |
| 产品应用 | Flow-Cyt=1:50-100 Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 抗体来源 | Rat |
| 亚型 | Rat IgG2b, k |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 48 kDa |
| 实际分子量 | 55kDa |
| 储存液 | 0.01M TBS (pH7.4). |
| 研究领域 | Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Adaptive Immunity > T Cells > CD Immunology > Immune System Diseases > Antiviral Signaling > HIV-related Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Dendritic Cell Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage |
| 亚基 | Associates with LCK. Binds to HIV-1 gp120 and to P4HB/PDI and upon HIV-1 binding to the cell membrane, is part of P4HB/PDI-CD4-CXCR4-gp120 complex. Interacts with HIV-1 Envelope polyprotein gp160 and protein Vpu. Interacts with Human Herpes virus 7 capsid proteins. Interacts with PTK2/FAK1; this interaction requires the presence of HIV-1 gp120. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum. |
| 翻译后修饰 | Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts. |
| 相似性 | Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the Human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1:50-100} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Evaluation of Immunogenicity of Rat ES-Cell Derived Endothelial Cells
would enable their general use in allogeneic settings and therefore supply an unrestricted source. Based on conflicting data in terms of immunogenicity published for mouse and human ES-derived cells, the rat model was used to complement the knowledge
Production of Monoclonal Antibodies in Swine
the somatogenic effect of porcine growth hormone (pGH) when administered in an experimental rat model (1 ,2 ). However, the concern of this type of approach was that the repeated injections of swine with mouse MAb would induce antimouse Ig responses
The OP9-DL1 System: Generation of T-Lymphocytes from Embryonic or Hematopoietic Stem Cells In Vitro
N 3M5, Canada 1 Corresponding author (jczp@sri.utoronto.ca ) INTRODUCTION Differentiation of mouse embryonic stem cells (ESCs) or hematopoietic stem cells (HSCs) from fetal liver or bone marrow into T-lymphocytes can be achieved in vitro
技术资料暂无技术资料 索取技术资料
