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500ug
| 产品编号 | bs-1780P |
| 英文名称 | CCRK Antibody Blocking Peptide |
| 中文名称 | 细胞周期相关激酶封闭多肽 |
| 英文别名 | CDK20; Cell cycle related kinase; p42; CAK kinase p42; CDCH; CDK activating kinase p42; Cell cycle related kinase; Cyclin dependent protein kinase H; Cyclin kinase activating kinase p42. CAK-kinase p42; Cyclin-dependent kinase 20; Cell cycle-related kinase; Cell division protein kinase 20. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases > Cdk Regulators Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases |
| 亚基 | Monomer. Interacts with BROMI. |
| 亚细胞定位 | Nucleus. Cytoplasm. Cell projection, cilium. |
| 相似性 | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain. |
| 功能 | Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009] |
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CCRK Antibody Blocking Peptide(bs-1780P)-500ug
¥880







