CCRK Antibody Blocking Peptide(bs-1780P)-500ug

CCRK Antibody Blocking Peptide

(bs-1780P)-500ug
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  • ¥880
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  • bs-1780P
  • 2025年10月16日
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      500ug

    产品编号bs-1780P
    英文名称CCRK Antibody Blocking Peptide
    中文名称细胞周期相关激酶封闭多肽
    英文别名CDK20; Cell cycle related kinase; p42; CAK kinase p42; CDCH; CDK activating kinase p42; Cell cycle related kinase; Cyclin dependent protein kinase H; Cyclin kinase activating kinase p42. CAK-kinase p42; Cyclin-dependent kinase 20; Cell cycle-related kinase; Cell division protein kinase 20.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases > Cdk Regulators

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases

    亚基Monomer. Interacts with BROMI.
    亚细胞定位Nucleus. Cytoplasm. Cell projection, cilium.
    相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
    功能Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009]

     

     

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