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- bs-17802P
- 2025年10月16日
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500ug
| 产品编号 | bs-17802P |
| 英文名称 | MRPL49 Antibody Blocking Peptide |
| 中文名称 | 线粒体核糖体蛋白L49封闭多肽 |
| 英文别名 | 39S ribosomal protein L49 mitochondrial; C11orf4; Chromosome 11 open reading frame 4; L49mt; MGC10656; Mitochondrial ribosomal protein L49; MRP L49; NeiGHBor of FAU; Next to FAU; NOF; NOF1; Protein NOF1; RM49. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Mitochondrial |
| 组织特异性 | Ubiquitous. |
| 相似性 | Belongs to the ribosomal protein L49em family. |
| 功能 | Mitochondria have their own translation system for production of 13 inner membrane proteins essential for oxidative phosphorylation. MRPL49 is a component of the large subunit of the mitochondrial ribosome that is encoded by the nuclear genome. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011] |
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MRPL49 Antibody Blocking Peptide(bs-17802P)-500ug
￥880
