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500ug
| 产品编号 | bs-0849P |
| 英文名称 | ApoA1 Antibody Blocking Peptide |
| 中文名称 | 载脂蛋白A1封闭多肽 |
| 英文别名 | Apo-AI; ApoA I; ApoA-I; APOA1_HUMAN; Apolipoprotein A-I(1-242); Apolipoprotein A1; Apolipoprotein A 1; Apolipoprotein AI; Apolipoprotein A I; Brp14; Ltw1; Lvtw1; Sep1; Sep2. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 亚基 | Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin. Interacts with NDRG1. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. |
| 翻译后修饰 | Palmitoylated. Phosphorylation sites are present in the extracelllular medium. |
| 相似性 | Belongs to the apolipoprotein A1/A4/E family. |
| 功能 | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008] |
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ApoA1 Antibody Blocking Peptide(bs-0849P)-500ug
¥880







