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- bs-17688P
- 2025年10月16日
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500ug
| 产品编号 | bs-17688P |
| 英文名称 | MMRN2 Antibody Blocking Peptide |
| 中文名称 | 细胞外基质糖蛋白MMRN2封闭多肽 |
| 英文别名 | Elastin microfibril interface located protein 3; Elastin microfibril interfacer 3; EMILIN-3; EndoGlyx-1 p125/p140 subunit; MMRN2; MMRN2_HUMAN; Multimerin-2. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Other ECM Proteins |
| 亚基 | Heteromer of p110, p125, p140 and p200 subunits;disulfide-linked. Interacts with VEGFA. |
| 亚细胞定位 | Secreted > extracellular space > extracellular matrix. |
| 组织特异性 | Endothelium. |
| 翻译后修饰 | N- and O-glycosylated. |
| 相似性 | Contains 1 C1q domain. Contains 1 EMI domain. |
| 功能 | Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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