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- Bioss
- bs-10496P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-10496P |
| 英文名称 | FBXO18 Antibody Blocking Peptide |
| 中文名称 | F-box蛋白家族FBXO18封闭多肽 |
| 英文别名 | Fbx18; FLJ14590; MGC131916; MGC141935; MGC141937; F box DNA helicase 1; F box only protein 18; F box protein, helicase, 18; F-box only protein 18, F-box DNA helicase 1; FBH1; FBX18_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > SCF Complex E3 Ligase Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding |
| 亚基 | Part of a SCF E3 ubiquitin ligase complex consisting of SKP1, CUL1, RBX1 and FBXO18. Interacts with SKP1. |
| 亚细胞定位 | Nuclear |
| 相似性 | Belongs to the helicase family. UvrD subfamily. Contains 1 F-box domain. |
| 功能 | DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | FBXO18 belongs to the F-box protein family, whose members share the F-box, an approximately 40 amino acid motif. It has both DNA-dependent ATPase and DNA unwinding activities.FBXO18 is a 1,043 amino acid protein encoded by the human gene FBXO18. FBXO18 belongs to the helicase family (UvrD subfamily) and contains one F-box domain. This nuclear protein is a DNA-dependent ATPase that unwinds double-stranded DNA in a 3' to 5' direction. FBXO18 also recognizes and binds to a variety of phosphorylated proteins and promotes their ubiquitination and degradation. It also interacts with Skp1 in the SCF E3 ubiquitin ligase complex consisting of Skp1, CUL-1, Rbx1 and FBXO18. |
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FBXO18 Antibody Blocking Peptide(bs-10496P)-500ug
￥880
