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- bs-10295P
- 2025年10月16日
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500ug
| 产品编号 | bs-10295P |
| 英文名称 | SLC12A5 Antibody Blocking Peptide |
| 中文名称 | 神经细胞钾氯离子转运蛋白封闭多肽 |
| 英文别名 | Electroneutral potassium chloride cotransporter 2; Electroneutral potassium-chloride cotransporter 2; Erythroid K Cl cotransporter 2; Erythroid K-Cl cotransporter 2; Furosemide sensitive K Cl cotransporter; hKCC2; K-Cl cotransporter 2; KCC 2; KCC2; KIAA1176; Neuronal K Cl cotransporter; Neuronal K-Cl cotransporter; S12A5; S12A5_HUMAN; SLC12A5; Solute carrier family 12 (potassium chloride transporter) member 5; Solute carrier family 12 member 5. |
| 纯化方法 | HPLC |
| 亚基 | Homomultimer and heteromultimer with other K-Cl cotransporters. Interacts with AP2A1. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Brain specific. Detected in neuronal cells. |
| 相似性 | Belongs to the SLC12A transporter family. |
| 功能 | Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008] |
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SLC12A5 Antibody Blocking Peptide(bs-10295P)-500ug
￥880
