IL17F Antibody Blocking Peptide(bs-10267P)-500ug

IL17F Antibody Blocking Peptid

e(bs-10267P)-500ug
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  • bs-10267P
  • 2025年10月16日
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      500ug

    产品编号bs-10267P
    英文名称IL17F Antibody Blocking Peptide
    中文名称白介素17F封闭多肽
    英文别名Interleukin 17F;Cytokine ML-1;IL-17F,IL17F_HUMAN;Interleukin-17F;CANDF6;ML1.
    纯化方法HPLC
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic inhibitory factors

    Cardiovascular > Angiogenesis > Cytokines > Interleukin

    Cardiovascular > Angiogenesis > Inhibitors

    Immunology > Innate Immunity > Cytokines > Interleukins

    亚基Homodimer; disulfide-linked.
    亚细胞定位Secreted.
    组织特异性Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
    相似性Belongs to the IL-17 family.
    功能Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料IL-17F is a member of IL-17 family of structurallyrelated cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F is a homodimer of two 133 amino acid chains that are secreted by activated CD4+ Tcells and activated monocytes. The biological activities mediated by IL-17F are similar to those of IL-17. IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony stimulating factor. It can also regulate cartilage matrix turnover, stimulate PBMC and T cell proliferation, and inhibit angiogenesis. This recombinant human IL-17F is produced by human cells. Biological activity: The activity was measured by its ability to induce IL-6 expression in the NHDF adult fibroblasts. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

     

     

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