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500ug
| 产品编号 | bs-10267P |
| 英文名称 | IL17F Antibody Blocking Peptide |
| 中文名称 | 白介素17F封闭多肽 |
| 英文别名 | Interleukin 17F;Cytokine ML-1;IL-17F,IL17F_HUMAN;Interleukin-17F;CANDF6;ML1. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic inhibitory factors Cardiovascular > Angiogenesis > Cytokines > Interleukin Cardiovascular > Angiogenesis > Inhibitors Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚基 | Homodimer; disulfide-linked. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in activated, but not resting, CD4+ T-cells and activated monocytes. |
| 相似性 | Belongs to the IL-17 family. |
| 功能 | Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IL-17F is a member of IL-17 family of structurallyrelated cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F is a homodimer of two 133 amino acid chains that are secreted by activated CD4+ Tcells and activated monocytes. The biological activities mediated by IL-17F are similar to those of IL-17. IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony stimulating factor. It can also regulate cartilage matrix turnover, stimulate PBMC and T cell proliferation, and inhibit angiogenesis. This recombinant human IL-17F is produced by human cells. Biological activity: The activity was measured by its ability to induce IL-6 expression in the NHDF adult fibroblasts. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |
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IL17F Antibody Blocking Peptide(bs-10267P)-500ug
¥880







