phospho-gamma Adducin (Ser693) Antibody Blocking Peptide(bs-10223P)-500ug

phospho-gamma Adducin (Ser693)

Antibody Blocking Peptide(bs-10223P)-500ug
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  • ¥1080
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  • bs-10223P
  • 2025年10月16日
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      500ug

    产品编号bs-10223P
    英文名称phospho-gamma Adducin (Ser693) Antibody Blocking Peptide
    中文名称磷酸化内收蛋白gamma封闭多肽
    英文别名ADD3; ADDG_HUMAN; ADDL; Adducin 3 (gamma); Adducin 3; Adducin-like protein 70; Gamma-adducin.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway

    Tags & Cell Markers > Subcellular Markers > Cytoskeleton > Actin

    亚基Heterodimer of an alpha and a gamma subunit.
    亚细胞定位Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
    组织特异性Isoform 1 is ubiquitously expressed.
    翻译后修饰Sumoylated.
    相似性Belongs to the aldolase class II family. Adducin subfamily.
    功能Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

     

     

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