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- bs-9805P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-9805P |
| 英文名称 | SLC35F6 Antibody Blocking Peptide |
| 中文名称 | 2号染色体开放阅读框18封闭多肽 |
| 英文别名 | ANT2 binding protein; ANT2BP; Chromosome 2 open reading frame 18; FLJ20555; S35F6_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor biomarkers |
| 亚基 | Interacts with SLC25A5. |
| 亚细胞定位 | Mitochondrion. Lysosome membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in pancreatic ductal adenocarcinoma (PDAC) (at protein level). Strongly expressed in prostate and thyroid. Weakly expressed in lung, heart, liver and kidney. |
| 相似性 | Belongs to the SLC35F solute transporter family. Contains 1 EamA domain. |
| 功能 | Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C2orf18 is a 371 amino acid multi-pass membrane protein that contains one DUF6 domain and is encoded by a gene that maps to human chromosome 2p23.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes. |
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SLC35F6 Antibody Blocking Peptide(bs-9805P)-500ug
￥880
