- ￥880
- Bioss
- bs-10036P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-10036P |
| 英文名称 | REG4 Antibody Blocking Peptide |
| 中文名称 | 再生基因蛋白4封闭多肽 |
| 英文别名 | Gastrointestinal secretory protein; GISP; REG IV; REG like protein; Regenerating gene type IV; Regenerating islet derived family member 4; Regenerating islet derived protein 4 precursor; REGIV; RELP; REG4_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor biomarkers Immunology > Secreted Molecules > Other secreted molecules |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. |
| 相似性 | Contains 1 C-type lectin domain. |
| 功能 | May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Reg IV is part of the regenerating gene family within the C-type lectin superfamily. This family is involved in liver, pancreatic, gastric and intestinal cell proliferation and differentiation. Reg IV is a 158-amino acid secretory protein implicated in cell regeneration and/or survival with a definite growth stimulating effect on pancreatic beta cells. It is highly expressed in colorectal, gastric, prostate and other types of cancer. Reg IV-positive tumor cells display different phenotypes including mucus-secreting, enterocyte-like, and undifferentiated. |
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REG4 Antibody Blocking Peptide(bs-10036P)-500ug
￥880
