- ￥580 - 5680
- Bioss
- bs-49194P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
100ug/20ug/500ug
| 规格： | 100ug | 产品价格： | ￥1880.0 |
|---|---|---|---|
| 规格： | 20ug | 产品价格： | ￥580.0 |
| 规格： | 500ug | 产品价格： | ￥5680.0 |
| 产品编号 | bs-49194P |
| 英文名称 | Recombinant Chinese cobra Cytotoxin 1 protein, His |
| 中文名称 | 重组眼镜蛇蛇毒蛋白 |
| 英文别名 | 3SA1_NAJAT; Cytotoxin 1 · Naja atra (Chinese cobra); Cytotoxin1; Recombinant Chinese cobra Cytotoxin 1 protein, His |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 22.2 |
| 实际分子量 | 27 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | 20mM Tris-HCl (pH8.0) with 0.25mM NaCl. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation (By similarity).It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity and inhibits protein kinases C (PubMed:8448165).It also binds with high affinity to heparin (PubMed:17685633). |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 51% as determined by reducing SDS-PAGE.
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Recombinant Chinese cobra Cytotoxin 1 protein, His(bs-49194P)-100ug/20ug/500ug
￥580 - 5680
