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ELAVL3 Antibody Blocking Pepti

de(bs-4068P)-500ug
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  • ¥880
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  • bs-4068P
  • 2025年10月16日
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      500ug

    产品编号bs-4068P
    英文名称ELAVL3 Antibody Blocking Peptide
    中文名称副肿瘤综合症小脑变性相关蛋白封闭多肽
    英文别名ELAV (embryonic lethal abnormal vision Drosophila) like 3; ELAV-like protein 3 isoform 1; ELAV-like protein 3; Hu antigen C; ELAV like protein 3; ELAVL3; Hu antigen C; HUC; HUCL; Paraneoplastic cerebellar degeneration associated antigen; Paraneoplastic limbic encephalitis antigen 21; DKFZp547J036; MGC20653; PLE21; ELAV3_HUMAN.
    纯化方法HPLC
    研究领域

    Neuroscience > Cell Type Marker > Neuron marker > Soma marker

    Neuroscience > Neurology process > Neural Signal Transduction

    组织特异性Brain specific.
    相似性Belongs to the RRM elav family.
    Contains 3 RRM (RNA recognition motif) domains.
    功能Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq].

     

     

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