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LRP15 Antibody Blocking Peptid

e(bs-9509P)-500ug
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  • ¥880
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  • bs-9509P
  • 2025年10月16日
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      500ug

    产品编号bs-9509P
    英文名称LRP15 Antibody Blocking Peptide
    中文名称富含亮氨酸重复序列LRP15封闭多肽
    英文别名LRP 15; LRP-15; Leucine rich repeat containing 3B; Leucine-rich repeat protein LRP15; Leucine-rich repeat-containing protein 3B; LRC3B_HUMAN; LRRC3B; MGC102927.
    纯化方法HPLC
    研究领域

    Cancer > Oncoproteins/suppressors > Tumor suppressors

    Cardiovascular > Blood > Blood Pressure regulation

    Cardiovascular > Blood > Coagulation > Regulatory

    Neuroscience > Neurology process > Neurogenesis

    亚细胞定位Membrane; Single-pass membrane protein (Potential).
    相似性Belongs to the LRRC3 family.
    Contains 3 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers.

     

     

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