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- bs-20796P
- 2025年10月16日
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500ug
| 产品编号 | bs-20796P |
| 英文名称 | CD14 Antibody Blocking Peptide |
| 中文名称 | 内毒素受体封闭多肽 |
| 英文别名 | CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte Differentiation Antigen 14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_HUMAN; Myeloid cell-specific leucine-rich glycoprotein. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Cell Type Markers > CD > Myeloid Cells Immunology > Innate Immunity > TLR Signaling Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > CD markers ELISA kits Stem Cells > Endothelial Progenitors > Endothelial Markers Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Neutrophil Lineage Stem Cells > Mesenchymal Stem Cells > Negative Markers |
| 亚基 | Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4. |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. |
| 相似性 | Contains 11 LRR (leucine-rich) repeats. |
| 功能 | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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