- ￥880
- Bioss
- bs-9315P
- 2025年10月16日
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500ug
| 产品编号 | bs-9315P |
| 英文名称 | MKLP1 Antibody Blocking Peptide |
| 中文名称 | 有丝分裂驱动蛋白样1封闭多肽 |
| 英文别名 | CHO 1; CHO1; KIF 23; KIF23; KIF23_HUMAN; Kinesin family member 23; Kinesin like 5; Kinesin like protein 5; Kinesin like protein KIF 23; Kinesin like protein KIF23; Kinesin-like protein 5; Kinesin-like protein KIF23; KNS L5; KNSL 5; KNSL5; Mitotic kinesin like 1; Mitotic kinesin like protein 1; Mitotic kinesin-like protein 1; MKLP 1. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Cardiogenesis > Myocardial regeneration Cell Biology > Cell Cycle > Cell Division > Spindle Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin-like |
| 亚基 | Heterotetramer of two molecules each of RACGAP1 and KIF23. Found in the centralspindlin complex composed of RACGAP1 and KIF23. Interacts with RACGAP1; the interaction is direct. Interacts with ECT2 and PRC1. Interacts with ANXA11 during cytokinesis. Interacts with BIRC6/bruce and USP8/UBPY. |
| 亚细胞定位 | Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interzone of mitotic spindles. |
| 翻译后修饰 | Ubiquitinated. Deubiquitinated by USP8/UBPY. |
| 相似性 | Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. |
| 功能 | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in two transcript variants encoding two different isoforms. |
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MKLP1 Antibody Blocking Peptide(bs-9315P)-500ug
￥880
