ODF3 Antibody Blocking Peptide(bs-9406P)-500ug

ODF3 Antibody Blocking Peptide

(bs-9406P)-500ug
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  • ¥880
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  • bs-9406P
  • 2025年10月16日
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      500ug

    产品编号bs-9406P
    英文名称ODF3 Antibody Blocking Peptide
    中文名称肿瘤/睾丸抗原135封闭多肽
    英文别名Cancer/testis antigen 135; CT135; hSHIPPO; odf3; ODF3A_HUMAN; Outer dense fiber of sperm tails 3; Outer dense fiber of sperm tails protein 3; Outer dense fiber protein 3; SHIPPO1; Sperm tail protein SHIPPO 1; Sperm tail protein SHIPPO1; TISP50; Transcript induced in spermiogenesis protein 50.
    纯化方法HPLC
    亚细胞定位Cytoplasm. Expressed in the cytoplasmic lobe of spermatids.
    组织特异性Testis-specific.
    相似性Belongs to the ODF3 family.
    Contains 2 STPGR (Sperm-tail PG-rich) repeats.
    功能Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.Constituting the main cytoskeletal structure of spermatid flagella, outer dense fibers (ODFs) add elastic recoil, stiffness and protection against shear forces during sperm movement. Human ODFs consist of approximately 10 major and at least 15 minor proteins. The major proteins of the ODF include Odf1, Odf2, and Odf3, which compose a family of proteins that are preferentially expressed during mammalian spermiogenesis. Odf3 (outer dense fiber protein 3), also known as sperm tail protein SHIPPO 1 and TISP50 (transcript induced in spermiogenesis protein 50), is a 254 amino acid protein that is expressed during the latter part of spermatogenesis in flagella of elongated spermatids and mature sperm. Odf proteins are directed to their exact subcellular location by Spags, which are characterized as chaperone-like Odf-binding molecules. There are two isoforms of Odf3 that are produced as a result of alternative splicing events.

     

     

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