- ￥880
- Bioss
- bs-9376P
- 2025年10月16日
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500ug
| 产品编号 | bs-9376P |
| 英文名称 | MURF3 Antibody Blocking Peptide |
| 中文名称 | 肌肉特定环指蛋白3封闭多肽 |
| 英文别名 | MURF 3; MURF; MURF-3; MuRF3; Muscle specific RING finger protein 3; Muscle specific RING finger protein; Muscle specific RING finger protein homolog; Muscle-specific RING finger protein 3; Muscle-specific RING finger protein; Ring finger protein 30; RNF30; TRI54_HUMAN; TRIM 54; TRIM54; RNF28; Tripartite motif containing 54; tibody Tripartite motif-containing protein 54. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Contractility > Contractile Proteins > Myosins Cardiovascular > Heart > Contractility > Contractile Proteins > Troponin Cardiovascular > Heart > Hypertrophy Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase Epigenetics and Nuclear Signaling > Cell cycle > Ubiquitin ligases Epigenetics and Nuclear Signaling > Ubiquitin & Ubiquitin Like Modifiers > E3 Ubiquitin Ligases |
| 亚基 | Homooligomer and heterooligomer. Interacts with tubulin (By similarity). Interacts with TRIM63 and probably with TRIM55. |
| 亚细胞定位 | Cytoplasm, cytoskeleton (By similarity). Cytoplasm, myofibril, sarcomere, Z line (By similarity). Note=Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity). |
| 组织特异性 | Specifically expressed in heart and skeletal muscle. |
| 相似性 | Contains 1 B box-type zinc finger. Contains 1 COS domain. Contains 1 RING-type zinc finger. |
| 功能 | May bind and stabilize microtubules during myotubes formation (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MuRF3, also designated tripartite motif-containing 54 (TRIM54) or ring finger protein 30 (RNF30), interacts with tubulin and stabilizes microtubules duing myotube formation. It is a cytoplasmic protein the localizes to the Z-lines in skeletal muscles, while MuRF2 localizes to the sarcomeric M-band in cardiomyocytes. MuRF3 shares 77% and 65% sequence identity with MuRF1 and MuRF2, respectively. MuRF1-3 share a conserved N-terminal RING domain and zinc-binding B-box motif, and two coiled-coil dimerization motif boxes, in their central regions. |
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MURF3 Antibody Blocking Peptide(bs-9376P)-500ug
￥880
