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500ug
| 产品编号 | bs-9375P |
| 英文名称 | MYCBP2 Antibody Blocking Peptide |
| 中文名称 | MYC结合蛋白2封闭多肽 |
| 英文别名 | Pam/highwire/rpm-1 protein; Phr1; MYC binding protein 2; PAM; Pam, highwire, rpm 1; Protein associated with Myc; Probable E3 ubiquitin-protein ligase MYCBP2; Myc-binding protein 2; Pam/highwire/rpm-1 protein; Protein associated with Myc; MYCB2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase Signal Transduction > Second Messenger > Nucleotide Messenger > cAMP |
| 亚基 | Interacts with MYC. Interacts with TSC2 (tuberin) when TSC2 is in complex with TSC1 (hamartin). Interacts with FBXO45. |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Expressed in all tissues examined, expression is exceptionally abundant in brain and thymus. Colocalizes with TSC1 and TSC2 along the neurites and in the growth cones. Colocalized with TSC1 in one of the filopodial extensions at the tip of a growth cone. |
| 相似性 | Belongs to the highwire family. Contains 1 B box-type zinc finger. Contains 1 DOC domain. Contains 1 filamin repeat. Contains 5 RCC1 repeats. Contains 1 RING-type zinc finger. |
| 功能 | Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MYCBP2 belongs to the highwire family. It is a probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. MYCBP2 may function as a facilitator or regulator of transcriptional activation by MYC and have a role during synaptogenesis. There are two different isoforms. |
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MYCBP2 Antibody Blocking Peptide(bs-9375P)-500ug
¥880







