MYCBP2 Antibody Blocking Peptide(bs-9375P)-500ug

MYCBP2 Antibody Blocking Pepti

de(bs-9375P)-500ug
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  • bs-9375P
  • 2025年10月16日
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      500ug

    产品编号bs-9375P
    英文名称MYCBP2 Antibody Blocking Peptide
    中文名称MYC结合蛋白2封闭多肽
    英文别名Pam/highwire/rpm-1 protein; Phr1; MYC binding protein 2; PAM; Pam, highwire, rpm 1; Protein associated with Myc; Probable E3 ubiquitin-protein ligase MYCBP2; Myc-binding protein 2; Pam/highwire/rpm-1 protein; Protein associated with Myc; MYCB2_HUMAN.
    纯化方法HPLC
    研究领域

    Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase

    Signal Transduction > Second Messenger > Nucleotide Messenger > cAMP

    亚基Interacts with MYC. Interacts with TSC2 (tuberin) when TSC2 is in complex with TSC1 (hamartin). Interacts with FBXO45.
    亚细胞定位Nuclear
    组织特异性Expressed in all tissues examined, expression is exceptionally abundant in brain and thymus. Colocalizes with TSC1 and TSC2 along the neurites and in the growth cones. Colocalized with TSC1 in one of the filopodial extensions at the tip of a growth cone.
    相似性Belongs to the highwire family.
    Contains 1 B box-type zinc finger.
    Contains 1 DOC domain.
    Contains 1 filamin repeat.
    Contains 5 RCC1 repeats.
    Contains 1 RING-type zinc finger.
    功能Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料MYCBP2 belongs to the highwire family. It is a probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. MYCBP2 may function as a facilitator or regulator of transcriptional activation by MYC and have a role during synaptogenesis. There are two different isoforms.

     

     

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