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- bs-9367P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-9367P |
| 英文名称 | PSMD6 Antibody Blocking Peptide |
| 中文名称 | 蛋白酶调解因子6封闭多肽 |
| 英文别名 | 26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; KIAA0107; p42A; P44S10; PFAAP4; PSMD6_HUMAN; Phosphonoformate immuno-associated protein 4; Proteasome (prosome, macropain) 26S subunit, non-ATPase, 6; Proteasome regulatory particle subunit p44S10; Rpn7; S10 antibody SGA-113M. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Proteasome |
| 亚基 | Component of the PA700 complex. |
| 亚细胞定位 | Proteasome complex. |
| 组织特异性 | Overexpressed in hepatocellular carcinomas. |
| 相似性 | Belongs to the proteasome subunit S10 family. Contains 1 PCI domain. |
| 功能 | Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. Proteasome 26S S10 is a non-ATPase subunit of the 19S regulator. It acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20. |
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PSMD6 Antibody Blocking Peptide(bs-9367P)-500ug
￥880
