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- bs-7912P
- 2025年10月16日
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| 产品编号 | bs-7912P |
| 英文名称 | GAK protein Antibody Blocking Peptide |
| 中文名称 | 细胞周期蛋白G相关激酶封闭多肽 |
| 英文别名 | Cyclin G associated kinase; Cyclin-G-associated kinase; EC 2.7.11.1; FLJ16629; FLJ40395; GAK; GAK protein; GAK_HUMAN; MGC99654. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Kinases/Phosphatases Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases |
| 亚细胞定位 | Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion (Probable). Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focals adhesions. |
| 组织特异性 | Ubiquitous. Highest in testis. |
| 相似性 | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 C2 tensin-type domain. Contains 1 J domain. Contains 1 phosphatase tensin-type domain. Contains 1 protein kinase domain. |
| 功能 | Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.Tissue specificity: Ubiquitous. Highest in testis. |
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文献和实验Peptide Microarrays for Serum Antibody Diagnostics
Peptide microarrays are useful instruments for miniaturized high-throughput, high-content immunoassays. The substitution of linear epitopes of the protein antigen with short, synthetic peptides is virtually a straightforward approach
Antibody Epitope Mapping Using SPOT Peptide Arrays
types of peptide libraries and their applications are described: protein sequence-derived scans of overlapping peptides (peptide scans) used to locate epitopes within the protein sequence, truncation libraries used to identify the minimal peptide length
Blocking Immunodominant Epitopes by Competitive Deselection
The development of combinatorial antibody (Ab) libraries displayed on the surface of phage has led to the production of a wide range of human monoclonal antibodies (MAbs) against a plethora of viral antigens (Ag) (1 -5
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