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- Bioss
- bs-9261P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9261P |
| 英文名称 | RNF185 Antibody Blocking Peptide |
| 中文名称 | 环指蛋白185封闭多肽 |
| 英文别名 | FLJ38628; Ring finger protein 185; RN185_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Interacts with ATG5 and BNIP1. |
| 亚细胞定位 | Mitochondrion outer membrane; Multi pass membrane protein |
| 相似性 | Contains 1 RING-type zinc finger. |
| 功能 | Mitochondrial E3 ubiquitin-protein ligase that regulatesselective mitochondrial autophagy by mediating 'Lys-63'-linkedpolyubiquitination of BNIP1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF185 (ring finger protein 185), also known as FLJ38628, is a 192 amino acid multi-pass membrane protein containing one RING-type zinc finger. Two RNF185 isoforms exist as a result of alternative splicing, and the gene encoding RNF185 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. |
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RNF185 Antibody Blocking Peptide(bs-9261P)-500ug
￥880
