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ALOXE3 Antibody Blocking Pepti

de(bs-7856P)-500ug
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  • ¥880
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  • bs-7856P
  • 2025年10月16日
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      500ug

    产品编号bs-7856P
    英文名称ALOXE3 Antibody Blocking Peptide
    中文名称过氧化氢异构酶ALOXE3封闭多肽
    英文别名ALOXE3; Arachidonate lipoxygenase 3; e LOX 3; E LOX; e-LOX-3; eLOX3; Epidermal lipoxygenase; Epidermis-type lipoxygenase 3; Lipoxygenase 3; LOXE3_HUMAN.
    纯化方法HPLC
    研究领域

    Cell Biology > Cell Cycle > Cell differentiation

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Lipid metabolism

    Tags & Cell Markers > Cell Type Markers > Epi / Endo-thelial

    组织特异性Predominantly expressed in skin.
    相似性Belongs to the lipoxygenase family. Contains 1 lipoxygenase domain. Contains 1 PLAT domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.Tissue specificity:Predominantly expressed in skin.Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.

     

     

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