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- Bioss
- bs-7850P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7850P |
| 英文名称 | TTK Antibody Blocking Peptide |
| 中文名称 | 单极纺锤体蛋白激酶1封闭多肽 |
| 英文别名 | Dual specificity protein kinase TTK; ECSTY kinase; ESK; FLJ38280; hMPS1; Monopolar Spindle 1 Like 1; Mps 1; Mps-1; MPS1L1; Phosphotyrosine Picked Threonine Kinase; PYT; TTK; TTK Protein Kinase; TTK_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Spindle Cell Biology > Cell Cycle > Kinases/Phosphatases Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases |
| 组织特异性 | Present in rapidly proliferating cell lines. |
| 相似性 | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. |
| 功能 | Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Mps1 (TTK) is a tyrosine and serine/threonine dual-specificity kinase required for centrosome duplication and the spindle checkpoint and has recently been shown to have a role in centrosome duplication. Alterations to Mps1 have been associated with cell transformation and chromosome instability in different tumor models. It is present in rapidly proliferating cell lines. |
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TTK Antibody Blocking Peptide(bs-7850P)-500ug
￥880
