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- Bioss
- bs-9215P
- 2025年10月16日
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500ug
| 产品编号 | bs-9215P |
| 英文名称 | CST5 Antibody Blocking Peptide |
| 中文名称 | 胱抑素D/半胱氨酸蛋白酶抑制剂D封闭多肽 |
| 英文别名 | CST 5; CST5; Cystatin 5; Cystatin5; Cystatin-5; CystatinD; Cystatin D; Cysteine proteinase inhibitor; MGC71922; CYTD_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Monomer. |
| 亚细胞定位 | Secreted |
| 组织特异性 | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in parotid gland but not in seminal vesicle, prostate, epididymis, testis, ovary, placenta, thyroid, gastric corpus, small intestine, liver, or gall bladder tissue. |
| 相似性 | Belongs to the cystatin family. |
| 功能 | Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes. |
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CST5 Antibody Blocking Peptide(bs-9215P)-500ug
￥880
