SERPINB11 Antibody Blocking Peptide(bs-9212P)-500ug

SERPINB11 Antibody Blocking Pe

ptide(bs-9212P)-500ug
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  • ¥880
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  • bs-9212P
  • 2025年10月16日
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      500ug

    产品编号bs-9212P
    英文名称SERPINB11 Antibody Blocking Peptide
    中文名称丝氨酸蛋白酶抑制剂B11封闭多肽
    英文别名EPIPIN; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 11 antibody Serpin B11 antibody Serpin peptidase inhibitor clade B (ovalbumin) member 11 antibody SERPINB11d antibody SERPINB11e antibody SERPINB11f; SPB11_HUMAN.
    纯化方法HPLC
    亚细胞定位Cytoplasmic
    组织特异性Detected in a restricted number of tissues, including lung, placenta, prostate, and tonsil.
    相似性Belongs to the serpin family. Ov-serpin subfamily.
    功能Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SerpinB11 (serpin peptidase inhibitor, clade B (ovalbumin), member 11), also known as EPIPIN or SERPIN11, is a 392 amino acid cytoplasmic protein that belongs to the Ov-serpin subfamily and serpin family. Like other members of the serpin family, SerpinB11 has been identified as a noninhibitory intracellular protein. The gene encoding SerpinB11 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.

     

     

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