- ￥880
- Bioss
- bs-9209P
- 2025年10月16日
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500ug
| 产品编号 | bs-9209P |
| 英文名称 | SERPINA10 Antibody Blocking Peptide |
| 中文名称 | 丝氨酸蛋白酶抑制剂A10封闭多肽 |
| 英文别名 | Protein Z dependent protease inhibitor; Protein Z dependent protease inhibitor precursor; Protein Z-dependent protease inhibitor; PZ dependent protease inhibitor; PZ-dependent protease inhibitor; PZI; serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 10 ; Serpin A10; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 10; SERPINA 10; SERPINA10; ZPI; ZPI_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Blood > Serum Proteins Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Serine protease inhibitors > SERPINs |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed by the liver and secreted in plasma. |
| 翻译后修饰 | Phosphorylation sites are present in the extracelllular medium. |
| 相似性 | Belongs to the serpin family. |
| 功能 | Inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ZPI, also known as SERPINA10 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10) or PZI, is a 444 amino acid secreted protein that functions as a Protein Z-dependent protease inhibitor. Expressed by the liver, ZPI is secreted into the plasma where, in the presence of calcium, Protein Z and phospholipids, it inhibits the activated pro-coagulation factors X and XI (Factor X and Factor XI). This inhibition helps properly regulate intravenous blood clotting. ZPI, a member of the serpin protein family, contains five potential N-linked glycosylation sites and a tyrosine at position 387 which, when disrupted, renders ZPI inactive. Defects in the gene encoding ZPI may increase susceptibility to venous thrombosis, the formation of blood clots within a vein. |
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SERPINA10 Antibody Blocking Peptide(bs-9209P)-500ug
￥880
