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| 产品编号 | bs-9208P |
| 英文名称 | CSPP1 Antibody Blocking Peptide |
| 中文名称 | 中心体和纺锤体极相关蛋白1封闭多肽 |
| 英文别名 | Centrosome and spindle pole associated protein 1; CSPP 1; CSPP; FLJ22490; FLJ38886; CSPP1_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with PLEKHG6 |
| 亚细胞定位 | Cytoplasm; cytoskeleton; centrosome. Cytoplasm; cytoskeleton; spindle. Note: Associated with mitotic spindles. |
| 组织特异性 | Detected in testis. |
| 翻译后修饰 | Phosphorylated. Phosphorylation increases in colcemide-treated cells. |
| 功能 | May play a role in cell-cycle-dependent microtubule organization. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Centrosomes are dynamic organelles involved in many aspects of cell function and growth. Centrosomes act as microtubule organizing centers, and provide a site for concerted regulation of cell cycle progression. Duplication of centrosomes occurs once during each cell cycle and requires proper mitotic spindle formation and chromosome segregation. Defects in centrosome duplication or function are linked to many human diseases, including various forms of cancer. The centrosome and spindle pole-associated protein 1 (CSPP1) interacts with centrosomes and microtubules and may play a role in the regulation of G(1)/S-phase progression and spindle assembly. Two isoforms of CSPP1 exist as a result of alternative splicing events. Isoform 1 expression increases throughout the cell cycle and peaks in G2/M phase, whereas isoform 2 expression is highest in G1 phase and decreases thereafter. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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