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500ug
| 产品编号 | bs-9197P |
| 英文名称 | IGSF5 Antibody Blocking Peptide |
| 中文名称 | 免疫球蛋白超家族成员5封闭多肽 |
| 英文别名 | GSF5; IgSF5; IGSF5_HUMAN; Immunoglobulin superfamily 5 like; Immunoglobulin superfamily member 5; JAM-4; Junctional adhesion molecule 4. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with MAGI1 at tight junctions, forms a tripartite complex with NPHS1 (By similarity). Interacts with LNX1 isoform 2 via its PDZ 2 domain, it may also interact with other isoforms containing this domain (By similarity). |
| 亚细胞定位 | Cell membrane; Single-pass membrane protein (By similarity). Cell junction, tight junction (By similarity). |
| 相似性 | Belongs to the immunoglobulin superfamily. Contains 2 Ig-like V-type (immunoglobulin-like) domains. |
| 功能 | Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells. |
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IGSF5 Antibody Blocking Peptide(bs-9197P)-500ug
¥880







