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IGSF3 Antibody Blocking Peptid

e(bs-9196P)-500ug
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  • ¥880
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  • bs-9196P
  • 2025年10月16日
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      500ug

    产品编号bs-9196P
    英文名称IGSF3 Antibody Blocking Peptide
    中文名称免疫球蛋白超家族成员3封闭多肽
    英文别名EWI 3; EWI3; Glu Trp Ile EWI motif containing protein 3; Immunoglobin superfamily member 3; Immunoglobulin superfamily member 3; KIAA0466; MGC117164; V8 antibody; IGSF3_HUMAN.
    纯化方法HPLC
    亚细胞定位Membrane; Single-pass type I membrane protein
    组织特异性It is expressed in a wide range of tissues with high expression in placenta, kidney and lung.
    相似性Contains 8 Ig-like C2-type (immunoglobulin-like) domains.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule.

     

     

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