MPP9/MPHOSPH9 Antibody Blocking Peptide(bs-7812P)-500ug

MPP9/MPHOSPH9 Antibody Blockin

g Peptide(bs-7812P)-500ug
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  • ¥880
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  • bs-7812P
  • 2025年10月16日
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      500ug

    产品编号bs-7812P
    英文名称MPP9/MPHOSPH9 Antibody Blocking Peptide
    中文名称有丝分裂细胞周期蛋白MPP9封闭多肽
    英文别名M phase phosphoprotein 9; MPP-9: MPP 9; MPP9; MPP9_HUMAN.
    纯化方法HPLC
    亚细胞定位Cytoplasm > cytoskeleton > centrosome > centriole. Golgi apparatus membrane. Localizes to the distal and proximal end of centriole pairs in duplicated centrosomes. In ciliated cells, localizes to the distal and proximal end of daughter centriole and proximal of the mother centriole but not in the distal end of the mother centriole.
    翻译后修饰Phosphorylated in M (mitotic) phase.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase-promoting factor (MPF). In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs), also known as MPHOSPHs, permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. MPP9 (M-phase phosphoprotein 9), also known as MPHOSPH9, is a 1,031 amino acid peripheral membrane protein of the Golgi apparatus that exists as two alternatively spliced isoforms. The gene encoding MPP9 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p.

     

     

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