VGLL3 Antibody Blocking Peptide(bs-9184P)-500ug

VGLL3 Antibody Blocking Peptid

e(bs-9184P)-500ug
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  • ¥880
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  • bs-9184P
  • 2025年10月16日
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      500ug

    产品编号bs-9184P
    英文名称VGLL3 Antibody Blocking Peptide
    中文名称转录辅助因子退变样蛋白3封闭多肽
    英文别名Colon carcinoma related protein; Vestigial like 3 (Drosophila); VGL 3; VGL-3; VGL3; VGLL3_HUMAN.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Co-factors

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    亚细胞定位Nucleus
    组织特异性Enriched in placenta.
    相似性Belongs to the vestigial family.
    功能May act as a specific coactivator for the mammalian TEFs
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The transcriptional enhancer factor-1 (TEF-1) family of transcription factors regulate tissue-specific gene expression in muscle and placenta. The mechanism whereby TEF-1 confers tissue specificity depends largely on the interaction of TEF-1 with tissue-specific cofactors. Transcription cofactor Vgl-3 (vestigial-like protein 3), also known as colon carcinoma related protein, is a 326 amino acid nuclear protein that may act as a specific coactivator for the mammalian transcription elongation factors. Both Vgl-1 and Vgl-3 are enriched in placenta, whereas Vgl-2 is expressed in differentiating somites and branchial arches during embryogenesis and is skeletal-muscle specific in adult tissues. There are two isoforms of Vgl-3 that are produced as a result of alternative splicing events.

     

     

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