- ￥880
- Bioss
- bs-7781P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7781P |
| 英文名称 | CDC123 Antibody Blocking Peptide |
| 中文名称 | 细胞分裂周期蛋白CDC123封闭多肽 |
| 英文别名 | C10orf7; CD123_HUMAN; CDC123; Cell division cycle protein 123 homolog; D123; HT 1080; HT-1080; Protein D123; PZ32. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis. |
| 相似性 | Belongs to the CDC123 family. |
| 功能 | Required for S phase entry of the cell cycle |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Required for S phase entry of the cell cycle.The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers. |
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CDC123 Antibody Blocking Peptide(bs-7781P)-500ug
￥880
