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- Bioss
- bs-9143P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9143P |
| 英文名称 | RNF141 Antibody Blocking Peptide |
| 中文名称 | 锌指蛋白230封闭多肽 |
| 英文别名 | C3HC4 Like Zinc Finger Protein; FDZF2; Ring Finger Protein 141; ZFP 26; Zinc Finger Protein 230; Zinc finger protein FDZF2; RNF141; RN141_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Membrane |
| 组织特异性 | soform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients. |
| 相似性 | Contains 1 RING-type zinc finger. |
| 功能 | May be involved in spermatogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF141 (ring finger protein 141), also known as ZFP26 or ZNF230, is a 230 amino acid protein that contains one RING-type zinc finger. Expressed as two isoforms (isoform 1 and isoform 2) due to alternative splicing events, RNF141 is thought to function as a transcription factor during spermatogenesis. While isoform 2 is expressed in brain, heart, pancreas, kidney and skeletal muscle, isoform 1 is expressed primarily in testis, suggesting that isoform 1 functions during spermatogenesis. In addition, RNF141 is not expressed in azoospermic (infertile) men, further implicating an important role for RNF141 in testis development and male fertility. |
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RNF141 Antibody Blocking Peptide(bs-9143P)-500ug
￥880
