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- Bioss
- bs-20421P
- 2025年10月16日
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500ug
| 产品编号 | bs-20421P |
| 英文名称 | COUP-TF1 Antibody Blocking Peptide |
| 中文名称 | 转录因子COUP1封闭多肽 |
| 英文别名 | Chicken ovalbumin upstream promoter 1; chicken ovalbumin upstream promoter; COT1_HUMAN; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP TF1; EAR-3; EAR3; ERBAL3; NR2F1; Nuclear receptor subfamily 2 group F member 1; SVP44; TCFCOUP1; TFCOUP1; Transcription factor COUP 1; V ERBA related protein EAR 3; V-erbA-related protein 3. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Orphan Nuclear Receptors Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Binds DNA as dimer; homodimer and probable heterodimer with NR2F6. Interacts with COPS2. |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the nuclear hormone receptor family. NR2 subfamily.
Contains 1 nuclear receptor DNA-binding domain. |
| 功能 | Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | COUP transcription factors have been cloned in several species and identified as orphan members of the steroid/thyroid hormone receptor superfamily. COUP-TFI (also designated COUP or EAR-3) and ARP-1 (also designated COUP-TFII) exhibit highly regulated and overlapping expression in most tissues. COUP-TFs are highly expressed in the developing and central nervous system, suggesting that these factors may be important in neural development and differentiation. COUP-TFs can compete for binding to response elements which are common to other members of this family, including RAR, RXR, PPAR, HNF-4, VDR and TR. They have been shown to act as negative regulators as well as initiators of transcription. |
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COUP-TF1 Antibody Blocking Peptide(bs-20421P)-500ug
￥880
