- ￥880
- Bioss
- bs-9114P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9114P |
| 英文名称 | BAGE2 + BAGE3 Antibody Blocking Peptide |
| 中文名称 | 肿瘤/睾丸抗原2.2/睾丸抗原2.3封闭多肽 |
| 英文别名 | B melanoma antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2; CT2.2; BAGE2_HUMAN; B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2 member 3; CT2.3. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas. |
| 相似性 | Belongs to the BAGE family. |
| 功能 | Unknown. Candidate gene encoding tumor antigens. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. |
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BAGE2 + BAGE3 Antibody Blocking Peptide(bs-9114P)-500ug
￥880
