- ￥880
- Bioss
- bs-9037P
- 2025年10月16日
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500ug
| 产品编号 | bs-9037P |
| 英文名称 | PDZK3 Antibody Blocking Peptide |
| 中文名称 | 前列腺癌激活蛋白封闭多肽 |
| 英文别名 | Activated in prostate cancer protein; AIPC; KIAA0300; Likely ortholog of rat plakophilin related armadillo repeat protein interacting PDZ protein antibody PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain containing protein 2; PDZ domain containing protein 3; PDZD2; PDZK 2; PDZK2; PDZK-2; PDZK 3; PDZK3; PDZK-3; PIN1; Plakophilin related armadillo repeat protein interacting PDZ protein like; Rat plakophilin related armadillo repeat protein interacting PDZ protein like; PDZD2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Intracellular Signaling > Adapters |
| 亚基 | Interacts with SCN10A, CTNND2 and PKP4 (By similarity). |
| 亚细胞定位 | Cytoplasmic, Endoplasmic reticulum, Nuclear and Secreted |
| 组织特异性 | Isoform 2 is expressed (at protein level) in prostate and many prostate tumors. |
| 翻译后修饰 | A secreted form is produced by caspase-mediated proteolytic cleavage (By similarity). |
| 相似性 | Contains 6 PDZ (DHR) domains. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. PDZK3 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, the PDZK3 gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. |
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PDZK3 Antibody Blocking Peptide(bs-9037P)-500ug
￥880
