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- Bioss
- bs-7669P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-7669P |
| 英文名称 | ANXA2R Antibody Blocking Peptide |
| 中文名称 | 膜粘连蛋白2受体封闭多肽 |
| 英文别名 | LOC389289; Annexin 2 receptor; Annexin II receptor; Annexin-2 receptor; ANXA2R; AX2R_HUMAN; AXIIR; C5orf39; Chromosome 5 open reading frame 39. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Annexins Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins |
| 组织特异性 | Widely expressed. Highly expressed in lymphocytes. Expressed in both resting CD4(+) and CD8(+) T-cells. |
| 功能 | May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ANXA2R (annexin-2 receptor), also known as AX2R or C5orf39, is a 193 amino acid protein that is widely expressed and may act as an annexin II receptor on marrow stromal cells to induce osteoclast formation. In addition, ANXA2R is highly expressed in lymphocytes and is also found in resting CD4+ and CD8+ T cells. The gene encoding ANXA2R maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
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ANXA2R Antibody Blocking Peptide(bs-7669P)-500ug
￥880
