ISLR2 Antibody Blocking Peptide(bs-9025P)-500ug

ISLR2 Antibody Blocking Peptid

e(bs-9025P)-500ug
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  • ¥880
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  • bs-9025P
  • 2025年10月16日
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      500ug

    产品编号bs-9025P
    英文名称ISLR2 Antibody Blocking Peptide
    中文名称ISLR2蛋白封闭多肽
    英文别名Immunoglobulin superfamily containing leucine-rich repeat protein 2; Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein; ISLR2_HUMAN.
    纯化方法HPLC
    亚基Homomultimer. Interacts with NTRK1/TrkA (By similarity).
    亚细胞定位Cell membrane; Single-pass membrane protein (By similarity).
    相似性Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 5 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
    功能Required for axon extension during neural development (By similarity).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.

     

     

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