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500ug
| 产品编号 | bs-9025P |
| 英文名称 | ISLR2 Antibody Blocking Peptide |
| 中文名称 | ISLR2蛋白封闭多肽 |
| 英文别名 | Immunoglobulin superfamily containing leucine-rich repeat protein 2; Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein; ISLR2_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Homomultimer. Interacts with NTRK1/TrkA (By similarity). |
| 亚细胞定位 | Cell membrane; Single-pass membrane protein (By similarity). |
| 相似性 | Contains 1 Ig-like (immunoglobulin-like) domain. Contains 5 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. |
| 功能 | Required for axon extension during neural development (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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