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- Bioss
- bs-7697P
- 2025年10月16日
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500ug
| 产品编号 | bs-7697P |
| 英文名称 | BS69/Adenovirus 5 E1A binding protein Antibody Blocking Peptide |
| 中文名称 | 腺病毒5结合蛋白BS69/骨形态发生蛋白受体相关分子1封闭多肽 |
| 英文别名 | Adenovirus 5 E1A binding protein; Bone morphogenetic protein receptor associated molecule 1; BRAM1; BS69 variant 1; BS69 variant 2; BS69 variant 3; BS69 variant 4; Zinc finger MYND domain containing 11; ZMYND11. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Cycle Inhibitors Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription Epigenetics and Nuclear Signaling > Transcription > RNA polymerase Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Immunology > Immune System Diseases > Antiviral Signaling |
| 亚基 | Interacts (via MYND-type zinc finger) with NCOR1. Interacts (via MYND-type zinc finger) with human adenovirus early E1A protein (via PXLXP motif); this interaction inhibits E1A mediated transactivation. Interacts (via MYND-type zinc finger) with Epstein-Barr virus EBNA2 protein (via PXLXP motif). Interacts (via MYND-type zinc finger) with EZH2. Interacts with E2F6. |
| 亚细胞定位 | Nucleus. Chromosome. Note=Associates with chromatin and mitotic chromosomes. |
| 组织特异性 | Ubiquitous. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. Ubiquitinated, leading to proteasomal degradation. |
| 相似性 | Contains 1 bromo domain.
Contains 1 MYND-type zinc finger. Contains 1 PHD-type zinc finger. Contains 1 PWWP domain. |
| 功能 | Corepressor of transcription (Probable). May be involved in chromatin remodeling through association with several remodeling factors. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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BS69/Adenovirus 5 E1A binding protein Antibody Blocking Peptide(bs-7697P)-500ug
￥880
