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500ug
| 产品编号 | bs-9007P |
| 英文名称 | RCBTB1 Antibody Blocking Peptide |
| 中文名称 | 鸟嘌呤核苷酸交换因子封闭多肽 |
| 英文别名 | Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; CLLD7; CLLL7 protein; Guanine nucleotide exchange factor; broad-complex, tramtrack and bric a brac; Hypothetical protein FLJ39335; RCBT1_HUMAN; Rcbtb1; RCC1 and BTB domain-containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Proto-oncogenes |
| 亚细胞定位 | Nucleus (Potential). |
| 组织特异性 | Ubiquitously expressed |
| 相似性 | Contains 2 BTB (POZ) domains. Contains 6 RCC1 repeats. |
| 功能 | May be involved in cell cycle regulation by chromatin remodeling. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The BTB domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. RCBTB1 (regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1), also known as GLP, CLLD7, CLLL7 or E4.5, is a 531 amino acid protein that localizes to the nucleus and contains two BTB (POZ) domains and six RCC1 repeats. Expressed ubiquitously, RCBTB1 is thought to be involved in cell cycle regulation, specifically via chromatin remodeling. The gene encoding RCBTB1 maps to a region on human chromosome 13 that is frequently deleted in B-cell chronic lymphocytic leukemia, suggesting a possible role for RCBTB1 in tumor suppression. |
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RCBTB1 Antibody Blocking Peptide(bs-9007P)-500ug
¥880







