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500ug
| 产品编号 | bs-7609P |
| 英文名称 | DUSP2 Antibody Blocking Peptide |
| 中文名称 | 双特异性磷酸酶2封闭多肽 |
| 英文别名 | Dual specificity phosphatase 2; Dual specificity protein phosphatase 2; Dual specificity protein phosphatase PAC 1; DUSP 2; PAC 1; PAC1; Serine/threonine specific protein phosphatase; DUS2_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in hematopoietic tissues. |
| 相似性 | Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain. Contains 1 tyrosine-protein phosphatase domain. |
| 功能 | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis. |
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DUSP2 Antibody Blocking Peptide(bs-7609P)-500ug
¥880







