- ￥880
- Bioss
- bs-20217P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-20217P |
| 英文名称 | CRHR1 Antibody Blocking Peptide |
| 中文名称 | 促肾上腺皮质激素释放因子受体1封闭多肽 |
| 英文别名 | CRFR1_HUMAN; Corticotropin-releasing factor receptor 1; CRF-R-1; CRF-R1; CRFR-1; Corticotropin-releasing hormone receptor 1; CRH-R-1; CRH-R1; CRF1. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Types of disease > Cancer Metabolism > Types of disease > Obesity Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis Neuroscience > Neurology process > Metabolism Signal Transduction > Signaling Pathway > Nuclear Signaling > Nuclear Hormone Receptors > Corticoid |
| 亚基 | Interacts (via N-terminal extracellular domain) with CRF and UCN. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe. |
| 翻译后修饰 | C-terminal Ser or Thr residues may be phosphorylated. |
| 相似性 | Belongs to the G-protein coupled receptor 2 family. |
| 功能 | This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neiGHBoring gene MGC57346. |
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CRHR1 Antibody Blocking Peptide(bs-20217P)-500ug
￥880
