NECAB2 Antibody Blocking Peptide(bs-9016P)-500ug

NECAB2 Antibody Blocking Pepti

de(bs-9016P)-500ug
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  • ¥880
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  • bs-9016P
  • 2025年10月16日
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      500ug

    产品编号bs-9016P
    英文名称NECAB2 Antibody Blocking Peptide
    中文名称突触结合蛋白2封闭多肽
    英文别名EF hand calcium binding protein 2; EF-hand calcium-binding protein 2; N-terminal EF-hand calcium-binding protein 2; NECA2_HUMAN; Necab2; EFCBP2; EF CBP2; Neuronal calcium binding protein 2; Neuronal calcium-binding protein 2; Stip 2; Stip-2; Stip2; Synaptotagmin interacting protein 2; Synaptotagmin-interacting protein 2.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    Neuroscience > Neurotransmission > Calcium Signaling > Calcium Binding Proteins

    亚细胞定位Cytoplasm (By similarity).
    组织特异性Expressed in brain
    相似性Contains 1 ABM domain.
    Contains 2 EF-hand domains.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

     

     

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