- ￥880
- Bioss
- bs-20290P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-20290P |
| 英文名称 | DRG1 Antibody Blocking Peptide |
| 中文名称 | GTP发育调控结合蛋白1封闭多肽 |
| 英文别名 | Developmentally regulated GTP binding protein 1; Developmentally-regulated GTP-binding protein 1; DRG 1; DRG-1; DRG1; DRG1_HUMAN; NEDD 3; NEDD-3; NEDD3; Neural precursor cell expressed developmentally down regulated protein 3; Neural precursor cell expressed developmentally down-regulated protein 3. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Cell Biology > Cell Cycle > Cell differentiation Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins |
| 亚基 | Interacts (via its C-terminal) with TAL1. Interacts with ZC3H15; the interaction forms a polysomal DRG1-DFRP1/ZC3H15 complex which provides protein stability to DRG1 possibly by blocking poly-ubiquitination. Interacts with STK16; the interaction phosphorylates STK16 |
| 亚细胞定位 | Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes. |
| 组织特异性 | High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. |
| 翻译后修饰 | Sumoylated by UBE2I in response to MEKK1-mediated stimuli. |
| 相似性 | Belongs to the GTP1/OBG family. Contains 1 G (guanine nucleotide-binding) domain. |
| 功能 | Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | May play a role in cell proliferation, differentiation and death.High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. |
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DRG1 Antibody Blocking Peptide(bs-20290P)-500ug
￥880
