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- bs-8861P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-8861P |
| 英文名称 | STOML2 Antibody Blocking Peptide |
| 中文名称 | 溴化丙胺太林相关蛋白2封闭多肽 |
| 英文别名 | EPB72 like protein 2; HSPC108; OTTHUMP00000021320; SLP 2; SLP2; SLP-2; Stomatin (EPB72) like 2; Stomatin like 2; Stomatin like protein 2; STOML2; STML2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins |
| 亚细胞定位 | Membrane; peripheral membrane protein. Cytoplasm. Associated with the cytoskeleton. |
| 组织特异性 | Ubiquitously expressed at low levels. |
| 相似性 | Belongs to the band 7/mec-2 family. |
| 功能 | STOML2 is similar in sequence to stomatin. It is a 356 amino acid protein with a calculated molecular mass of 38.5 kDa. STOML2 has 3 potential initiator sites, all sharing the same open reading frame. The STOML2 protein contains the cognate stomatin family consensus sequence, but it lacks the characteristic N-terminal hydrophobic domain and palmitoylation consensus sequence. STOML2 shares greatest sequence homology with stomatin and SLP1 in a region predicted to contain beta sheet and alpha helix structures. Northern blot analysis detected a 1.5 kb STOML2 transcript in all tissues examined, with highest levels in heart, liver, and pancreas. Western blot analysis detected STOML2 at apparent molecular masses of 45.5 kDa or 44.6 kDa in all human and mammalian cell lines and tissues examined, including red blood cells. Some cells also showed a faint band at about 34.3 kDa, which may represent translation from an alternate initiation site. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | STOML2 is a 356 amino acid member of the mec-2 family of proteins. Expressed ubiquitously at low levels, STOML2 is highly expressed in heart, liver and pancreas. STOML2 is localized to the cytoplasm with some distribution on the membrane. STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth in samples with different levels of STOML2 indicate that STOML2 could play a role in endometrial tumorigenesis. STOML2 is also thought to play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts. |
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STOML2 Antibody Blocking Peptide(bs-8861P)-500ug
￥880
