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- bs-8848P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-8848P |
| 英文名称 | SCCD Antibody Blocking Peptide |
| 中文名称 | 抑癌蛋白UBIAD1封闭多肽 |
| 英文别名 | UBIAD1; RP4-796F18.1; SCCD; TERE 1; tere1; Transitional epithelia response protein; Transitional epithelial response protein 1; UbiA prenyltransferase domain containing 1; UbiA prenyltransferase domain containing protein 1; UbiA prenyltransferase domain-containing protein 1; UBIA1_HUMAN; UBIAD 1; Ubiad1. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Tumor Suppressors Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚细胞定位 | Endoplasmic reticulum membrane. Cytoplasm. Nucleus. Mitochondrion. |
| 组织特异性 | Ubiquitously expressed. |
| 相似性 | Belongs to the ubiA prenyltransferase family. |
| 功能 | Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas, and is required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosyntetic enzyme: coenzyme Q10, also named ubiquinone, plays a important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein thought to be involved in cholesterol and phospholipid metabolism. Mutations in this gene are associated with Schnyder crystalline corneal dystrophy. [provided by RefSeq, Oct 2008] |
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SCCD Antibody Blocking Peptide(bs-8848P)-500ug
￥880
